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Download 100 Questions & Answers About Gastrointestinal Stromal by Ronald DeMatteo PDF

By Ronald DeMatteo

ISBN-10: 0763738387

ISBN-13: 9780763738389

ISBN-10: 1429492538

ISBN-13: 9781429492539

Even if you are a newly clinically determined GI Stromal sufferer, a survivor, or a chum or relative of both, this e-book bargains support. the one textual content to supply the doctor's and patient's perspectives, a hundred Questions & solutions approximately Gastrointestinal Stromal Tumors (GIST) delivers authoritative, useful solutions for your questions on treatments, post-treatment caliber of lifestyles, assets of aid, and masses extra. This e-book is a useful source for a person dealing with the actual and emotional turmoil of this scary ailment.

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Extra info for 100 Questions & Answers About Gastrointestinal Stromal Tumor(GIST)

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A small percentage, called KIT-negative GISTs, does not express KIT. The diagnosis of a KIT-negative GIST is very difficult and requires an expert pathologist who may need to perform molecular tests, such as tumor genotyping, to make the diagnosis. Because GIST is uncommon, some pathologists have little to no experience with diagnosing them. The results of mistaken diagnoses can be devastating, since the correct choice of treatment hinges on the correct diagnosis. It is estimated that about 5% of patients diagnosed with a GIST do not actually have a GIST.

Anyone considering alternative and complementary approaches needs to be aware of the potential for quackery, which is the promotion of methods or products that are known to be false or unproven. Quackery generally involves soliciting a person to buy a product at expensive prices and promotes it as free from side effects or with natural healing benefits. Quackery offers junk theories about disease treatment that may even seem plausible. In fact, the claims are often erroneous if not outrageous. Some quackery practices may be harmful to the patient, and the risks may not be initially apparent to the patient.

An exon 9 KIT mutation is found predominantly in GISTs that arise from the small intestines, whereas the various PDGFRA mutations occur mostly in the stomach, as do the most common GIST molecular subtype with exon 11 KIT mutations. About 90% of all GISTs carry a primary mutation in either the KIT or PDGFRA genes. A relationship exists between the location of the primary mutation and the patient’s likely response to imatinib, the first therapy against inoperable GISTs. Notably, GISTs with an exon 11 KIT mutation have the most durable benefits from imatinib.

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100 Questions & Answers About Gastrointestinal Stromal Tumor(GIST) by Ronald DeMatteo


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